Abstract
Aim: To study autonomic dysfunction in Asian Indian T2DM patients by heart rate variability and it's relation with body fat content, distribution and insulin resistance.Subjects and Methods: Subjects: 33 T2DM patients aged (46.96 ± 8.90 yrs), and 33 healthy controls aged (44.08 ± 9.15 yrs).Methods: Short-term heart rate variability (HRV) was measured by impedance plethysmograph recording of pulse wave in distal superficial arteries. Time domain and Frequency domain analysis of HRV was carried out. Time domain parameters (SDNN, rMSSD, pNN50) and frequency domain parameters (Total Power, LF power, HF Power, LF (nu), HF (nu), LF/HF Ratio) were determined. Body fat content and distribution was estimated by (DEXA). Insulin Resistance was assessed by HOMA-R. Student t test was used for comparison of parameters in two groups. Multiple regression was used to find out relation between parameters of adiposity and HRV.Results: Parameters rMSSD, pNN50, Total power, LF Power, HF Power were significantly lower in diabetics. Total power showed negative correlation with BMI and truncal fat (r=-.43; p
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
