Abstract

A well-focused beam of fast (2.5–25 keV) sulfur hexafluoride neutral molecules has been developed based upon the autoneutralizing sulfur hexafluoride gas-phase anion. This molecular beam has been used to sputter gas-phase ions from dry solids with excellent results from a wide range of materials that include plastics and pharmaceuticals. Most pharmaceuticals have yielded predominantly protonated parent ions, with fragments typical of the molecular structure. Detection limits for these pharmaceuticals are around 1 ng.

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