AUTOMATION OF MR BRAIN IMAGE CLASSIFICATION FOR MALIGNANCY DETECTION

Abstract

Magnetic resonance imaging (MRI) plays an integral role among the advanced techniques for detecting a brain tumor. The early detection of brain tumor with proper automation algorithm results in assisting oncologists to make easy decisions for diagnostic purposes. This paper presents an automatic classification of MR brain images in normal and malignant conditions. The feature extraction is done with gray-level co-occurrence matrix, and we proposed a feature reduction technique based on statistical test which is preceded by principal component analysis (PCA). The main focus of the work is to establish the statistical significance of the features obtained after PCA, thereby selecting significant feature values for subsequent classification. For that, a [Formula: see text]-test is performed which yielded a [Formula: see text]-value of 0.05. Finally, a comparative study using [Formula: see text]-nearest neighbor (kNN), support vector machine and artificial neural network (ANN)-based supervised classifiers is performed. In this work, we could achieve reasonably good sensitivity, specificity and accuracy for all the classifiers. The ANN classifier gives better performance with sensitivity of 97.33%, specificity of 97.42% and accuracy of 98.66% on the whole brain atlas database. The experimental results obtained are comparable to the other recent state-of-the-art.