Abstract

Informatics for Integrating Biology and the Bedside (i2b2) is an open source clinical data analytics platform used at more than 150 institutions for querying patient data. An i2b2 installation (called hive) comprises several i2b2 cells that provide different functionalities. Given the complex architecture of i2b2 installation, creating a working installation of the platform is challenging for new users. This is despite the availability of extensive documentation for i2b2 and access to a large and active mailing list community of i2b2 users. To address this problem, we have created an automated installation package, called i2b2-quickstart, which automatically downloads the latest i2b2 source code and dependencies, and compiles and configures the i2b2 cells to create a functional i2b2 hive installation. This package will serve as a convenient starting point and reference implementation that will facilitate researchers in the installation and exploration of the i2b2 platform.

Highlights

  • Informatics for Integrating Biology and the Bedside (i2b2) is an open source clinical data analytics platform used at more than 150 health care institutions for querying patient data

  • The availability of the automated installation scripts will serve as a ready reference that augments the detailed installation documentation.This rapid installation will be useful for infrastructure teams to efficiently instantiate new instances of i2b2 platform at different sites

  • This article reports on our i2b2 quickstart package, which aims to facilitate a rapid installation of the i2b2 platform

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Summary

Introduction

Informatics for Integrating Biology and the Bedside (i2b2) is an open source clinical data analytics platform used at more than 150 health care institutions for querying patient data. The initial funding for i2b2 came from the National Institutes of Health It has developed into an international project with many active developers coordinated by the i2b2 tranSMART foundation.[2,3] The goal of i2b2 project is to provide clinical investigators with the software tools necessary to collect, manage, and analyze project-related clinical research data. The project provides a software suite (i2b2 platform) to construct and manage the data, and the platform has been deployed at more than 200 sites worldwide for providing cohort-querying services to clinical researchers. The i2b2 platform is composed of multiple cells that communicate using XML web services. The ability to integrate disparate data types with varying dimensionality into a single cohesive software infrastructure enables i2b2 to form the backbone of large-scale clinical research projects.

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