Abstract

This study aims to accurately segment the right ventricle (RV) from cardiac MRI using a fully automatic learning-based method. The proposed method uses deep learning algorithms, i.e., convolutional neural networks and stacked autoencoders, for automatic detection and initial segmentation of the RV chamber. The initial segmentation is then combined with the deformable models to improve the accuracy and robustness of the process. We trained our algorithm using 16 cardiac MRI datasets of the MICCAI 2012 RV Segmentation Challenge database and validated our technique using the rest of the dataset (32 subjects). An average Dice metric of 82.5% along with an average Hausdorff distance of 7.85 mm were achieved for all the studied subjects. Furthermore, a high correlation and level of agreement with the ground truth contours for end-diastolic volume (0.98), end-systolic volume (0.99), and ejection fraction (0.93) were observed. Our results show that deep learning algorithms can be effectively used for automatic segmentation of the RV. Computed quantitative metrics of our method outperformed that of the existing techniques participated in the MICCAI 2012 challenge, as reported by the challenge organizers. Magn Reson Med 78:2439-2448, 2017. © 2017 International Society for Magnetic Resonance in Medicine.

Highlights

  • Boundaries of the ground-truth masks [16]

  • TrainingSet of the RV segmentation challenge (RVSC) database [6] was used for training only, and Test1Set and Test2Set were used for validation

  • Most of the challenges for right ventricle (RV) segmentation are due to the complex anatomy of the RV chamber

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Summary

Introduction

Boundaries of the ground-truth masks [16]. Compared with left ventricle (LV), the study of the right ventricle (RV) is a relatively young field. Graph-cut-based methods combined with distribution matching [19], shape-prior [20] and region-merging [21] were studied for RV segmentation. Overall, these methods suffer from a low robustness and accuracy, and require extensive user interaction. Motivated by these limitations, we developed an accurate, fast, robust and fully automated segmentation framework for cardiac MRI. To obtain good results, it is important to provide the algorithm with clean and accurate data and labels [38]

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