Abstract

Background: Auditory brainstem response (ABR) testing is an invasive electrophysiological auditory function test. Its waveforms and threshold can reflect auditory functional changes in the auditory centers in the brainstem and are widely used in the clinic to diagnose dysfunction in hearing. However, identifying its waveforms and threshold is mainly dependent on manual recognition by experimental persons, which could be primarily influenced by individual experiences. This is also a heavy job in clinical practice.Methods: In this work, human ABR was recorded. First, binarization is created to mark 1,024 sampling points accordingly. The selected characteristic area of ABR data is 0–8 ms. The marking area is enlarged to expand feature information and reduce marking error. Second, a bidirectional long short-term memory (BiLSTM) network structure is established to improve relevance of sampling points, and an ABR sampling point classifier is obtained by training. Finally, mark points are obtained through thresholding.Results: The specific structure, related parameters, recognition effect, and noise resistance of the network were explored in 614 sets of ABR clinical data. The results show that the average detection time for each data was 0.05 s, and recognition accuracy reached 92.91%.Discussion: The study proposed an automatic recognition of ABR waveforms by using the BiLSTM-based machine learning technique. The results demonstrated that the proposed methods could reduce recording time and help doctors in making diagnosis, suggesting that the proposed method has the potential to be used in the clinic in the future.

Highlights

  • Auditory brainstem response (ABR) is a global neural activity in the auditory brainstem centers evoked by acoustic stimulations

  • This study proposes a method of using the long short-term memory (LSTM) network to identify waves I, III, and V in the ABR waveform and proposes a new idea for the recognition of ABR characteristic waveforms by neural networks

  • The sequence input layer was used as the input of the potential value of 321 sampling points, and the data were passed to several LSTM or BiLSTM layers

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Summary

Introduction

Auditory brainstem response (ABR) is a global neural activity in the auditory brainstem centers evoked by acoustic stimulations. It can observe the functional status of the auditory nerve and lower auditory center and reflect the conduction ability of the brainstem auditory pathway [1, 2]. Identifying its waveforms and threshold is mainly dependent on manual recognition by experimental persons, which could be primarily influenced by individual experiences. This is a heavy job in clinical practice

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