Abstract

Analysis of arterial pulse waveforms is important for non-invasive diagnosis of cardiovascular functions. Large samples of IPG signal records of radial arterial pulse show presence of eight different types of shapes (morphological patterns) in the pulse waveforms. In this paper we present an efficient computational method for automatic identification of these morphological patterns. Our algorithm uses likelihood ratio of cumulative periodogram of pulse signals and some geometrical criteria. The algorithm is presented with necessary details on signal processing aspects. Results for a large sample of pulse records of adult Indian subjects show high accuracy of our algorithm in detecting pulse-morphology patterns. Variation of pulse-morphology with respect to time is also analyzed using this algorithm. We have identified some characteristic features of pulse-morphology variation in patients of certain cardiac problems, hypertension, and diabetes. These are found relevant and significant in terms of physiological interpretation of the associated shapes of pulse waveforms. Importance of these findings is highlighted along with discussion on overall scope of our study in automatic analysis of heart rate variability and in other applications for non-invasive prognosis/diagnosis.

Highlights

  • Arterial pulse signal can provide valuable diagnostic information about cardiovascular health

  • We have identified some characteristic features of pulse-morphology variation in patients of certain cardiac problems, hypertension, and diabetes

  • We have developed a computational method for automatic detection of specific types of morphological patterns in radial arterial pulse waveform using Fisher’s Ratio [20] and some geometrical parameters

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Summary

Introduction

Arterial pulse signal can provide valuable diagnostic information about cardiovascular health. Cent years have seen revived interest in development of instruments for pulse-signal recording and in detection and analysis of Heart Rate Variability and related noninvasive applications Modern research on pulse signals is mostly focused on analysis of Heart Rate Variability [12,13,14,15]. Wang and Xiang [16] had analyzed power spectra of four kinds of pulse signals in frequency-domain using Fast Fourier Transform (FFT). Their results had correlated certain harmonics with regularity and smoothness properties of the pulse signal waveform. O’Ruke [7] had presented pulse waveform analysis to study arterial stiffness. Important parameters for pulse waveform analysis were analyzed in [8,18] vis-à-vis in vivo cardiac functioning

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