Automatic Brain Responses to Pitch Changes in Congenital Amusia

Abstract

Congenital amusia is a lifelong disorder affecting the processing of pitch. This pitch deficit can be traced down to abnormal brain responses elicited by pitch changes smaller than a semitone in conditions requiring attention. Here, we use the mismatch negativity (MMN) to investigate pre-attentive pitch change detection in 10 amusics and eight matched controls. Results indicate similar MMN in amusics and controls, even for an eighth of a tone change, revealing that the amusic brain can process small pitch changes at a pre-attentive level. Thus, the pitch deficit in congenital amusia may be related to a problem of perceptual awareness.