Abstract
Aim to assess if the pattern of left ventricle (LV) volume curves variation using automatic border detection (ABD) can help in differentiation of desynchronized contraction. Methods patients (pts) with dilated cardiomyopathy were included (n = 41; 58.3±16.2 years). Currently accepted TDI and TM parameters were used to indicate LV desynchronization. On-line continuous LV volumes changing were recorded using ABD. Ejection time (ET ABD) was measured from ABD wave-forms as time interval between maximal and minimal volume variation during LV electromechanical systole. Ejection time index was derived as ratio ET ABD/RR interval (ETi ABD = ET/RR). Results 26 pts presented QRSd>120ms, 15 pts had QRSd 120ms, 8 pts QRSd<120ms). In these pts ET ABD was 232±42ms significantly smaller than in pts without asynchrony (323±27 ms, p=0.0001); difference in ETi ABD was: 27±8% vs 39.5±4%, p=0.0001; 12 pts undergone biventricular pacing and presented significant improvement in ETi ABD (26±4% vs 31±5%, p=0.001) and LV volume contraction pattern. Conclusion ABD can help in differentiation of ventricular asynchrony and may be used in the follow-up of multisite pacing.
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