Abstract

Cervical cancer leads to major death disease in women around the world every year. This cancer can be cured if it is initially screened and giving timely treatment to the patients. This paper proposes a novel methodology for screening the cervical cancer using cervigram images. Oriented Local Histogram Technique (OLHT) is applied on the cervical image to enhance the edges and then Dual Tree Complex Wavelet Transform (DT-CWT) is applied on it to obtain multi resolution image. Then, features as wavelet, Grey Level Co-occurrence Matrix (GLCM), moment invariant and Local Binary Pattern (LBP) features are extracted from this transformed multi resolution cervical image. These extracted features are trained and also tested by feed forward back propagation neural network to classify the given cervical image into normal and abnormal. The morphological operations are applied on the abnormal cervical image to detect and segment the cancer region. The performance of the proposed cervical cancer detection system is analyzed in the terms of sensitivity, specificity, accuracy, positive predictive value, negative predictive value, Likelihood Ratio positive, Likelihood ratio negative, precision, false positive rate and false negative rate. The performance measures for the cervical cancer detection system achieves 97.42% of sensitivity, 99.36% of specificity, 98.29% of accuracy, PPV of 97.28%, NPV of 92.17%, LRP of 141.71, LRN of 0.0936, 97.38 % precision, 96.72% FPR and 91.36% NPR. From the simulation results, the proposed methodology outperforms the conventional methodologies for cervical cancer detection and segmentation process.

Highlights

  • Most of the deaths are occurred around the world based on cancer

  • The performance of the proposed cervical cancer detection system is analyzed in the terms of sensitivity, specificity, accuracy, positive predictive value, negative predictive value, Likelihood Ratio positive, Likelihood ratio negative, precision, false positive rate and false negative rate

  • The performance measures for the cervical cancer detection system achieves 97.42% of sensitivity, 99.36% of specificity, 98.29% of accuracy, Positive Predictive Value (PPV) of 97.28%, Negative Predictive Value (NPV) of 92.17%, Likelihood Ratio Positive (LRP) of 141.71, Likelihood Ratio Negative (LRN) of 0.0936, 97.38 % precision, 96.72% False Positive Rate (FPR) and 91.36% NPR

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Summary

Introduction

Most of the deaths are occurred around the world based on cancer. Breast and Cervical cancers are the most live killing diseases of women patients in and around the world (Susan et al, 2018). The women patients who are affected by breast cancer, can check themselves, it can be detected in women patients at an earlier manner as depicted in Kwok et al, (2011). The cervical cancer is occurred in the women patient internally and it can be detected by scanning the internal region of the vagina. Human Papillomavirus (HPV) virus (NCCC, 2010) is the main cause of cervical cancer formation in women patients. This virus initially affects the cells in the cervical region of the women patients and spreads over the entire region of the cervix (Robbins et al, 2009).The women patients who are affected by cervical cancer, unable to check themselves, it cannot be detected at an earlier stage. The cervical cancer in women can be screened by either Pap smear test or Cervicogram test (Katz et al, 2010)

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