Abstract
Background The human interaction required for manual motion correction/contouring of cardiac perfusion series remains a significant obstacle to quantitative perfusion gaining a wider acceptance in clinical practice. The use of image registration for motion correction in perfusion data offers a considerable time saving. Numerous registration methods have been proposed, with evaluation limited to the image registration accuracy. However, the important clinical question is how do these methods affect diagnosis? The aim of this study is to evaluate perfusion series registration in terms of its affect on the diagnostic accuracy of myocardial ischaemia.
Highlights
The human interaction required for manual motion correction/contouring of cardiac perfusion series remains a significant obstacle to quantitative perfusion gaining a wider acceptance in clinical practice
Myocardial perfusion reserve (MPR) indices were calculated from the ratio of stress to rest myocardial blood flow (MBF) estimates
A DeLong, DeLong, Clarke-Pearson comparison was used to test for statistically significant differences in the area under the curve (AUC) values between the registered and manually corrected Receiver Operator Characteristic (ROC) curves
Summary
Automated registration of dynamic contrast enhanced DCE-MRI cardiac perfusion achieves comparable diagnostic accuracy to manual motion correction: a CE-MARC sub-study. Constantine Zakkaroff2*, Aleksandra Radjenovic, John D Biglands, Sven Plein, John P Greenwood, Derek R Magee. From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. 16-19 January 2014
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
