Automated Clinicopathologic Correlation Integrating Clinical Findings, Suspicions, Hematopathology Tests and Previous Records

Abstract

Abstract Introduction/Objective Conducting clinicopathologic correlation (CPC) to provide comprehensive diagnosis, prognosis/risk assessment, follow up and/or recommendations is essential in Hematopathology. The clinical findings/suspicions and medical history contribute in building a personalized diagnosis and prognosis, while comparing with the previous records is required for specialized follow-ups and progression assessment. HIPAA violation liability and changeable medical guidelines limit the "freelance outsourcing" of Hematopathology assistance/second opinion. The proposed electronic Hematopathologist assistant could play this role perfectly, because automation in Hematopathology is easier when compared with other medical specialties. This is because only visual sense is needed for Hematopathology review/examination while automating more than one sense is needed in medicine and surgery. Methods/Case Report Scalable, customizable and fully controlled system is developed harnessing the state-of-the-art technologies. The user selects specific answers in smart hierarchical choice lists about specimen types, medical history, clinical findings and suspicions. Then, the available current and previous results of the performed diagnostic and prognostic test panels are needed to be entered and dated. These panels include quantitative and qualitative parameters of the complete blood count (CBC), smear review, flow cytometry, immunohistochemistry, cytogenetics and/or molecular studies. Zero harm to the patients privacy is achieved, there is no personal information entered or needed. Results (if a Case Study enter NA) Based on the entered results, detailed interpretation for each test panel is created to explain how the generated comprehensive CPC is built. Furthermore, the CPC is concluded in one line, this is an informative and summative title for the case. The system is also used as a triage advisor, it suggests the useful parameters to be triaged considering the choosing wisely recommendations and providing the potential percentage of resulting positive/abnormal in similar specific cases. All possible generated test panel interpretations, CPCs and case titles are reviewed and validated. Conclusion This system generates preliminary versions for the Hematopathologist to review, leading to productivity increase with no medical liability or feeling fatigued and stressed. This also helps to increase the profitability and cover the shortage.