Automated Classification of Breast Cancer Lesions for Digitised Mammograms via Computer-Aided Diagnosis System

Abstract

Women with breast cancer have a high risk of death. Digitised mammograms can be used to detect the early stage of breast cancer. However, digitised mammograms suffer low contrast appearances that may lead to misdiagnosis. This paper proposes a Computer-Aided Diagnosis (CAD) system of automated classification of breast cancer lesions using a modified image processing technique of Fuzzy Anisotropic Diffusion Histogram Equalization Contrast Adaptive Limited (FADHECAL) incorporated with Multilevel Otsu Thresholding on digitised mammograms. Four main blocks were used in this CAD system, namely; (i) Pre-processing and Enhancement block; (ii) Segmentation block; (iii) Region of Interests (ROIs) Extraction block; and (iv) Classification block. The CAD system was tested on 30 digitised mammograms retrieved from the Mini-Mammographic Image Analysis Society (MIAS) database with various degrees of severity and background tissues. The proposed CAD system showed a high accuracy of 96.67% for the detection of breast cancer lesions.