Abstract
The sensitive detection of biomarker with high selectivity and accuracy is of remarkable significance for the early screening and clinical diagnosis of malignant cancer. Persistent phosphors play a role in illumination-free biosensing owing to their unparalleled optical properties, which produces long-lasting luminescence without the illumination to eliminate the interference of autofluorescence and scattering light from biological matrix. In this study, ZnGeO:Mo persistent luminescence nanorods (PLNRs) were prepared and showed tunable luminescence intensity and decay patterns. An excitation-free luminescent aptasensor was proposed for the detection of prostate specific antigen (PSA) by using ZnGeO:Mo PLNRs as probes and Au@Ag@SiO2 nanoparticles as quenchers. Under optimal conditions, the limit of detection for PSA was 9.2 pg mL-1. This work creates a possibility for the preparation of multiplex colored persistent luminescence nanomaterials with desired decay patterns for multiple bioassay and time-resolved fluoroimmunoassay.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
