Abstract

patients were male and 21 female. The mean age was 43 years (2775). Central venous catheter was used in 45 (78.9%) HSCTs. FNEs was detected in 54 (94.7%) HSCT. All the patients received antiviral and antifungal prophylaxis and antibacterial prophylaxis was used in 26 (46.7%) HSCT. In FNEs, 10.5% efficient pathogen microorganism was isolated from blood cultures. 66.7% of pathogens were gram-positive, 33.3% were gram-negative bacterias. 3.5% efficient pathogen microorganism was isolated from urine cultures, all of them were gram-negative bacterias. 14.0% efficient pathogen microorganism was isolated from catheter cultures, all of them were gram-positive bacterias. A pathogen was isolated in 8.8% of stem cell products. Serum galactomannan antigen (SGA) was detected positive in only one (1.7%) episodes and false positivity of SGA was not detected. CMV-DNA was positive in 8.8% episodes. Thirty HRCT was performed in FNEs. Pneumonia was detected 8.8% in all episodes. 40% of pneumonia that detected in HRCTs was fungal and no viral pneumonia was detected. Conclusion: It can supply useful additive for a better FEN management process if the medical centers follow their infection agents closely, perform CMV and SGA assays and modify their empiric antibiotic treatment policies in especially HSCT groups.

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