Autologous blood concentrates application for post-extractional wound healing after impacted inferior wisdom tooth removal

Abstract

Wisdom teeth extraction is the most common OMF surgical intervention. After the surgery, there might emerge some complications that persist even if all the indications recommended by the doctor were followed. Purpose: To settle, based on a prospective case–control research, the performance of platelet–rich fibrin, introduced as A–PRF into the socket, on clinical development after wisdom teeth removal. Materials and methods: 24 patients aged between 22 and 46 years old, with an mean age of 28,38±7,06, participated in this research. All of them had their impacted lower wisdom teeth extracted, assessed according to the Modified Parent Scale with extraction difficulty index III. The patients were divided into two groups, each with 12 patients: Case — patients who had A–PRF plugs introduced into the socket and Control — patients undergoing conventional treatment. The patients were examined after the surgery on day 1, 3, 7, 10 where three variables were analyzed — pain, based on the Numerical Pain Rating Scale, edema, according to the Laskin method and regeneration with the Landry index. Results and discussion: Patients in the experimental group presented a lower pain index, none of which reported severe pain. In the control group, one patient reported severe pain on the first postoperative day. Regeneration of the oral mucosa clinically was faster and without complications, compared to the control group, in which 2 patients presented post–extraction bleeding on the next day of the surgery. No significant differences were observed between the groups in the clinical appearance of facial edema. Conclusions: Fibrin clots introduced into the socket reduced the risk of post–extractional bleeding with positive signs of faster surgical wound healing, with less pain for patients in the experimental group compared to those in the control group, but studies in larger groups of patients are necessary due to the relatively small number of patients included in this study.