Abstract
Auto immune Hepatitis (AIH) with cholestatic jaundice is a rare entity. AIH is characterized by inflammatory changes in liver with the presence of circulating auto antibodies and hyperglobulinemia. Here we report a case of 67-years-old lady who presented with Acute autoimmune hepatitis with cholestatic jaundice with early accurate diagnosis and early initiation of corticosteroids recovered successfully. Even though it is very rare AIH should not be overlooked in patients with cholestatic jaundice without viral/drug induced hepatitis.
Highlights
Auto immune Hepatitis (AIH) is a rare chronic liver cell disease with interesting variety of clinical manifestations suspected based on the presentation, biochemical findings, specific serological tests and liver histology with exclusion of other causes of chronic liver cell disease
Though the typical finding of AIH is elevated liver enzymes than the elevation of bilirubin our patient’s presenting symptom was deep jaundice with higher elevation of bilirubin, as her imaging study revealed no biliary tract obstruction it excluded the biliary tract destruction by inflammation it was supported by prompt response to prednisolone in our case
Liver histology typically showed the features of AIH in the patient
Summary
Auto immune Hepatitis (AIH) with cholestatic jaundice is a rare entity. AIH is characterized by inflammatory changes in liver with the presence of circulating auto antibodies and hyperglobulinemia. We report a case of 67-years-old lady who presented with Acute autoimmune hepatitis with cholestatic jaundice with early accurate diagnosis and early initiation of corticosteroids recovered successfully. Even though it is very rare AIH should not be overlooked in patients with cholestatic jaundice without viral/drug induced hepatitis
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