Abstract

= Abstract = Drug-induced toxic hepatitis is a relatively common hepatic disease in children and it is usually self-limiting upon cessation of the offending drugs. Antituberculous drugs are well known for inducing hepatitis. Some cases of drug-induced hepatitis with autoimmune features have been reported; in these cases the offending drugs were usually methyldopa nitrofurantoin minocycline and interferon. The authors report the first case in Korea of drug-induced autoimmune hepatitis associated with thyroiditis and multiple autoantibodies that was induced by the antituberculous drugs isoniazid and rifampin. (Korean J Pediatr 2008;51:528-532

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