Abstract
During January–March 2011, diagnoses of hepatitis E virus (HEV) infection increased in Marseille University hospitals in southeastern France. HEV genotype 4, which is described almost exclusively in Asia, was recovered from 2 persons who ate uncooked pork liver sausage. Genetic sequences were 96.7% identical to those recently described in swine in Europe.
Highlights
In industrialized countries, most cases of hepatitis E virus (HEV) infection in humans are autochthonous [1]
Because 4 contacts of the 2 HEV genotype 4 (HEV-4)–infected case-patients ate some of the figatelli eaten by the case-patients (Tables 1, 2), we investigated whether these contacts had markers for HEV infection
We report a concurrent rise in testing for and diagnoses of HEV infections in Marseille during January–March 2011
Summary
We report a concurrent rise in testing for and diagnoses of HEV infections in Marseille during January–March 2011. This rise may reflect increased clinician awareness of HEV or an increased incidence of HEV infection that may have resulted from the use of improved tools for HEV diagnosis. HEV has increasingly been recognized as a possible cause of hepatitis in diverse clinical settings, including in solid-organ transplant recipients. 3 (27%) of the casepatients were solid-organ transplant recipients. This number suggests a high incidence of HEV infection among transplant recipients in the geographic area we studied, and it is consistent with the incidence (≈3.2/100 person-years) of HEV infection among organ transplant recipients in Toulouse in southwestern France [4].
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