Abstract
We report 3 confirmed autochthonous tick-borne encephalitis cases in Belgium diagnosed during summer 2020. Clinicians should include this viral infection in the differential diagnosis for patients with etiologically unexplained neurologic manifestations, even for persons without recent travel history.
Highlights
We report 3 confirmed autochthonous tick-borne encephalitis cases in Belgium diagnosed during summer 2020
Borrelia and TBE virus (TBEV) serology were added to the differential diagnosis, and TBEV antibodies were detected by immunofluorescence assay (IFA) performed on serum collected on day 20 after illness onset
The National Reference Centre (NRC) used Flavivirus Profile 2 (EUROIMMUN AG, https://www.euroimmun.com) mosaic IFA to detect TBEV IgM and IgG antibodies in serum from the 3 patients and in Cerebrospinal fluid (CSF) from 2 of them
Summary
We report 3 confirmed autochthonous tick-borne encephalitis cases in Belgium diagnosed during summer 2020. We report 3 confirmed autochthonous TBE cases, diagnosed at the National Reference Centre (NRC) for Arboviruses (Antwerp, Belgium) during summer 2020. Serum collected on day 5 after illness onset tested positive for TBEV IgM and IgG by immunofluorescence assay (IFA) performed at the NRC.
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