Abstract

Single cases of autochthonous visceral leishmaniasis are registered in the Crimea and Dagestan. The article presents the first case of autochthonous cutaneous leishmaniasis in an HIV infected resident of the Republic of Dagestan, where this disease had not previously been registered. The diagnosis was made on the basis of a parasitological study of material taken from an ulcer on the border between the upper lip and the right nostril. Examination of the patient revealed a high burden of HIV (4 473 014 copies/ml) and a low level of CD4+ (76×106/l; 9%), which indicated an advanced stage of HIV infection. The patient underwent antiretroviral therapy (treatment with amphotericin B), against which a good result was obtained. A decrease in viral load and an increase in the content of CD4 lymphocytes in the blood were noted. A scar has formed on the site of a leishmaniasis ulcer.

Highlights

  • В России единичные случаи аутохтонного висцерального лейшманиоза регистрируются на территории Крыма и Дагестана

  • Single cases of autochthonous visceral leishmaniasis are registered in the Crimea and Dagestan

  • The article presents the first case of autochthonous cutaneous leishmaniasis in an HIV infected resident of the Republic of Dagestan, where this disease had not previously been registered

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Summary

Introduction

В России единичные случаи аутохтонного висцерального лейшманиоза регистрируются на территории Крыма и Дагестана. В статье представлен первый случай аутохтонного кожного лейшманиоза у ВИЧ-инфицированного жителя Республики Дагестан, где раньше это заболевание не регистрировалось. Диагноз был установлен на основании паразитологического исследования материала, взятого из язвы на границе между верхней губой и правой ноздрей. При обследовании больного выявлена высокая нагрузка ВИЧ (4 473 014 копий/мл) и низкий уровень CD4+ (76×106/л; 9%), что свидетельствовало о продвинутой стадии ВИЧ-инфекции.

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