Abstract

54 patients with acute and “chronic” myocarditis were tested for autoantibodies and serum inhibition factors. 11 patients had a viral myocarditis, 17 a “chronic” myocarditis. By comparing the antibody pattern of sera of patients with defined viral myocarditis with those of patients with myocarditis of unknown etiology we could demonstrate that antisarcolemmal (ASA) and antiendothelial antibodies (AEA) are markers of a viral involvement in heart disease. 10 of the 11 patients with Coxsackie B and Influenza virus myocarditis demonstrated this pattern.

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