Abstract

In the current world pandemic situation, the contagious Novel Coronavirus Disease 2019 (COVID-19) has raised a real threat to human lives owing to infection on lung cells and human respiratory systems. It is a daunting task for the researchers to find suitable infection patterns on lung CT images for automated diagnosis of COVID-19. A novel integrated semi-supervised shallow neural network framework comprising a Parallel Quantum-Inspired Self-supervised Network (PQIS-Net) for automatic segmentation of lung CT images followed by Fully Connected (FC) layers, is proposed in this article. The proposed PQIS-Net model is aimed at providing fully automated segmentation of lung CT slices without incorporating pre-trained convolutional neural network based models. A parallel trinity of layered structure of quantum bits are interconnected using an N-connected second order neighborhood-based topology in the suggested PQIS-Net architecture for segmentation of lung CT slices with wide variations of local intensities. A random patch-based classification on PQIS-Net segmented slices is incorporated at the classification layers of the suggested semi-supervised shallow neural network framework. Intensive experiments have been conducted using three publicly available data sets, one for purely segmentation task and the other two for classification (COVID-19 diagnosis). The experimental outcome on segmentation of CT slices using self-supervised PQIS-Net and the diagnosis efficiency (Accuracy, Precision and AUC) of the integrated semi-supervised shallow framework is found to be promising. The proposed model is also found to be superior than the best state-of-the-art techniques and pre-trained convolutional neural network-based models, specially in COVID-19 and Mycoplasma Pneumonia (MP) screening.

Highlights

  • The world has suffered a lot in the recent pandemic due to the 2019 novel coronavirus disease (COVID-19) since its rapid outbreak from Wuhan, China

  • One of the data sets [35] contains total 2482 lung CT images with variable sizes and out of these, 1252 lung CT images are infected by COVID-19 and 1230 CT slices are not infected by COVID-19

  • The third data set employed in this experiment is the IEEE CCAP data set [37] collected from IEEE Data port which comprises five different sets of lung CT images (COVID-19, Viral Pneumonia (VP), Bacterial Pneumonia (BP), Mycoplasma Pneumonia (MP) and Normal lung)

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Summary

Introduction

The world has suffered a lot in the recent pandemic due to the 2019 novel coronavirus disease (COVID-19) since its rapid outbreak from Wuhan, China. There have been sharp rises in infected and suspected cases in almost all the countries in the world from the beginning of January 2020 as reported by World Health Organization [1]. Of coronavirus disease has inflicted a SARS-CoV-2 acute respiratory syndrome and has resulted in a new febrile respiratory tract illness. Despite imposition of various strict measures and physical isolation guidelines, the number of positive test cases is rising rapidly and as of today (02/02/2021), the total number of confirmed cases reported in the entire world is over 102.1 million [2].

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