Abstract

Thus, if you consider the overlapping aspects of autism and autoimmune disease, it raises the suggestion that the positive association of high SES and autism may have similar origins in factors affecting early immune dysregulation. Moreover, this scenario is consistent with differences in access to health care playing a role in autism, given that greater access to prenatal and neonatal health care often leads to decreased rates of bacterial infection, viral infection, and environmental pathogenic exposure, as well as higher antibiotic use, which in turn may be associated with higher levels of inflammation leading to increased autoimmune disease.

Highlights

  • Some autoimmune and inflammatory disorders, in particular type 1 diabetes, autoimmune thyroiditis, and asthma have been positively associated with high socioeconomic status (SES), and the study of SES and geographical clustering parallels that found in autism

  • Autism has been positively associated with high socioeconomic status (SES) in at least eight epidemiological studies from different populations and in different ethnic backgrounds [1,2,3,4,5,6,7,8], while two Scandinavian studies did not find that association [9,10]

  • The causal basis for these associations with autism are unclear, many autism studies have suggested that they may be related to access to health resources, in the context of higher income and/ or education, influencing increasing autism diagnosis [11,13]

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Summary

Introduction

Some autoimmune and inflammatory disorders, in particular type 1 diabetes, autoimmune thyroiditis, and asthma have been positively associated with high SES, and the study of SES and geographical clustering parallels that found in autism.

Results
Conclusion

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