Author’s reply

Abstract

The pathogenic mechanism(s) underlying the progressive nature of this unique form of anterior polar cataract remain uncertain. Dr. Christensen’s suggestion that this behavior is the result of a loss of cuboidal epithelium at the base of the pyramidal lesion is an equally valid interpretation of the histologic evidence presented in the article. It is our opinion that there were no differences in histologic findings between pyramidal and flat anterior polar cataracts, although the photomicrographs presented in the article do not fully illustrate this fact. Nevertheless, the concept that lens epithelial cell dysfunction is involved in pyramidal cataract formation and progressive cortical opacification is logically sound and entirely plausible. The authors also agree that the textbook reference cited in our discussion of anterior polar cataract histology may not have been ideally chosen, and we appreciate Dr. Christensen bringing an additional article to our attention and to that of the readers of Ophthalmology.