Abstract
We appreciate the editorial comment and agree with the editor's take-home message of our paper. 1 Quintana L. Ward A. Gerrin S.J. et al. Gleason misclassification rate is independent of number of biopsy cores in systematic biopsy [Editorial Comment]. Urology. 2016; Abstract Full Text Full Text PDF PubMed Scopus (21) Google Scholar Detection of high-grade prostate cancer is not likely to be improved by increasing the number of cores in systematic core biopsy. Instead, we need to adopt and further refine modern imaging techniques such as magnetic resonance imaging- or magnetic resonance imaging/transrectal ultrasound-fusion to detect high-grade tumor and to guide core biopsy. The editor raised two important issues. One is whether pathologists can define risk subgroups of Gleason pattern 4 and the second is whether the presence of any amount of Gleason pattern 4 on needle biopsy should be considered as “clinically significant” cancer.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
