Abstract

When faced with a diagnosis of putatively localized kidney cancer, patients and their physicians alike want to be able to understand both their risk of recurrence and their cancer-specific survival. Many preoperative nomograms, and other risk calculators, designed to answer precisely such questions, have focused on predominantly tumor-specific factors, such as tumor size, presence of presumed malignant lymphadenopathy, and specific radiographic features such as necrosis. Postoperative risk calculators also focus on a similar set of tumor-specific factors, and surgical pathology factors, in addition to variables subject to potential ascertainment bias such as performance status, and constitutional symptoms. These long-standing tools are certainly valuable.

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