Abstract
These comments are all very apt and important. Fortunately, in our described series of transrectal ultrasound (TR) biopsy, we had no serious infection cases, but sepsis, and or significant rectal bleeding remain potential risks of TR biopsy. The increasing frequency of adverse events have been important factors in the recommendations of various guideline panels in advising against Prostate-Specific Antigen (PSA) screening and early prostate cancer detection. With new PSA-based biomarkers and MRI, there have been tremendous improvements in our ability to identify the appropriate men for biopsy who have a high likelihood of finding clinically meaningful cancer, while avoiding invasive procedures on many with abnormal PSA from benign causes.
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