Austrian Syndrome in an Immunocompromised Patient—A Case Report

Carlos E Arias-Morales,Venkata Sandeep Koripalli,Razia Rehmani,Marjorie M Flores-Chang,Michelle Dahdouh,Shorabh Sharma

doi:10.3389/fmed.2020.00142

Carlos E Arias-Morales, Venkata Sandeep Koripalli + Show 4 more

Open Access

https://doi.org/10.3389/fmed.2020.00142

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Abstract

Austrian syndrome consists of a triad of endocarditis, meningitis, and pneumonia caused by Streptococcus pneumoniae. With the arrival of many antibiotic therapies, the disease remains rare, however, it can be overlooked due to the lack of awareness. We present a case of Austrian syndrome in an immunocompromised patient complicated by multiorgan failure.

Highlights

Austrian syndrome consists of a triad of endocarditis, meningitis, and pneumonia caused by Streptococcus pneumoniae [1]
Blood cultures collected before the initiation of antibiotic therapy grew Streptococcus pneumoniae sensitive to ceftriaxone and penicillin
Austrian syndrome consists of a triad of endocarditis, meningitis and pneumonia caused by S. pneumoniae

Summary

INTRODUCTION

Austrian syndrome consists of a triad of endocarditis, meningitis, and pneumonia caused by Streptococcus pneumoniae [1]. With the arrival of many antibiotic therapies, the disease remains rare, it can be overlooked due to the lack of awareness. Mortality in invasive pneumococcal disease appears to be increased in immunocompromised patients, especially HIV infected patients in whom the increase in mortality may be explained by the impaired humoral immunity that is needed to combat infections by encapsulated organisms, in this case, S. pneumoniae [2]. To the best of our knowledge, there are ∼ less than 60 cases reported in the medical literature. We present a case of Austrian syndrome in an immunocompromised patient complicated by multiorgan failure

CASE PRESENTATION

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AUTHOR CONTRIBUTIONS