Abstract
The quest for the use of plants in the management of reproductive hormone dysfunction prompted this research. This study explored the effects of <i>Ricinodendron heudelotti</i> seed ethanol extract on some male reproductive hormones. Twenty five male albino rats were used. The animals were grouped into five and each group had five (5) albino rats. The extract was processed from the seeds of <i>Ricinodendron heudelotti</i>. Group A served as control, group B animals were administered with 300mg/kg.bw, while groups C, D and E animals were administered 450, 600 and 750 mg/kg.bw of the extract respectively for twenty one days. The animals were sacrificed and their blood samples were collected for the assay of testosterone, Follicle stimulating hormone (FSH) and Luteinizing hormone (LH). From the results obtained, the serum testosterone level of the experimental animals showed a concentration dependent increase in all the extract administered groups when compared with the value of the control group. FSH and LH levels showed an increase statistically (p≤0.05) in comparison to the level of the control. <i>Ricinodendron heudelotti</i> seed extract effectively increased the reproductive hormones of the animals by increasing the serum Testosterone, FSH and LH levels, hence suggests its effectiveness in enhancement of the male reproductive function.
Highlights
Current increase in the rate of infertility in men has raised concern in the globe as it has led to various problems ranging from the home to the society at large
The presence of some metabolites found in plants [2, 3], enables them to carry out their therapeutic function through the additive or synergistic action of several chemical compounds acting at single or multiple target sites associated with a physiological process [4], the need to evaluate the plant of study for its assumed therapeutic value for the enhancement of reproductive functions in male wistar albino rats
This study investigates the augmentation potency of Ricinodendron heudelotii ethanol seed extract on some male reproductive hormones in wistar albino rats
Summary
Current increase in the rate of infertility in men has raised concern in the globe as it has led to various problems ranging from the home to the society at large. The presence of some metabolites found in plants [2, 3], enables them to carry out their therapeutic function through the additive or synergistic action of several chemical compounds acting at single or multiple target sites associated with a physiological process [4], the need to evaluate the plant of study for its assumed therapeutic value for the enhancement of reproductive functions in male wistar albino rats. The plant Ricinodendron heudelotii as revealed from study [5] contains phytochemicals that aids its potency to be used as a medicinal plant. Some of the medicinal properties of Ricinodendron heudelotii include; antimicrobial, antiulcer, antihyperlipidemic, and antioxidant biomarkers enhancer in diabetic oxidative stressed wistar albino rats [6]. The male reproductive hormones of concern in this study includes; testosterone, follicle stimulating hormone and luteinizing hormones
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