Abstract

The effect of the treatment of yeast cell walls (YCW) with PPD-induced lymphokines (LK) was studied. The rate of macrophage spreading increased 1 h and 24 h after incubation with YCW treated with 16-fold or 64-fold diluted LK. Phagocytosis was slightly enhanced after 1 h incubation. Cytostatic activity was obtained when incubated with YCW treated with 16-fold or 64-fold diluted LK, but not with LK of higher or lower dilution. Tumorinhibitory effect was observed when lymphoma cells were mixed with LK-treated YCW and inoculated s.c.

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