Abstract
The effects of propofol on auditory evoked potentials were studied in nine patients undergoing otorhinolaryngology surgery. After recording of basal evoked potentials patients received propofol 2 mg kg-1 over 2-3 min for induction of anaesthesia. Potentials were recorded every 10 min (T1, T2, T3). During T1, T2, T3, the infusion rates of propofol for maintenance of anaesthesia were respectively 7, 5 and 3 mg kg-1 h-1 consecutively. Middle latency component was affected markedly. Brainstem waves latencies I, III, V were increased significantly, while amplitude waves I, III, V remained constant.
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