Abstract
Emotional sensitivity and impulsivity could cause interpersonal conflicts and neuropsychiatric problems. Serotonin is correlated with behavioral inhibition and impulsivity. This study evaluated whether the loudness dependence of auditory evoked potential (LDAEP), a potential biological marker of central serotonergic activity, could reflect emotional sensitivity and impulsivity. A total of 157 healthy individuals were recruited, who performed LDAEP and Go/Nogo paradigms during electroencephalogram measurement. Barratt impulsivity scale (BIS), Conners’ Adult ADHD rating scale (CAARS), and affective lability scale (ALS) were evaluated. Comparison between low and high LDAEP groups was conducted for behavioural, psychological, and event-related potential (ERP) measures. The high LDAEP group showed significantly increased BIS, a subscale of the CAARS, ALS, and false alarm rate of Nogo stimuli compared to the low LDAEP group. LDAEP showed significant positive correlations with the depression scale, ALS scores, subscale of the CAARS and Nogo-P3 amplitude. In the source activity of Nogo-P3, the cuneus, lingual gyrus, and precentral gyrus activities were significantly increased in the high LDAEP group. Our study revealed that LDAEP could reflect emotional sensitivity and impulsivity. LDAEP, an auditory evoked potential could be a useful tool to evaluate emotional regulation.
Highlights
Individual personality traits such as emotional sensitivity and impulsivity could cause social conflicts, which can undesirably be manifested in criminal behavior or violence[1]
Scores of the Barratt impulsivity scale (BIS), Conners’ Adult Attention Deficit Hyperactivity Disorder (ADHD) rating scale (CAARS), and affective lability scale (ALS) were significantly greater in the high Loudness dependence auditory evoked potentials (LDAEP) group compared to the low LDAEP group
This study investigated whether nonclinical adults with higher LDAEP show higher emotional sensitivity and higher impulsivity
Summary
Individual personality traits such as emotional sensitivity and impulsivity could cause social conflicts, which can undesirably be manifested in criminal behavior or violence[1]. Recent meta-analysis reported that the components of event-related potential (ERP) of Go/Nogo tasks were associated with response inhibition[10]. N2 and P3 components, and accuracy rate from the Nogo task have mainly changed in patients with impulse control problems such as trichotillomania, antisocial personality disorder and Attention Deficit Hyperactivity Disorder (ADHD)[15,16,17]. Both Nogo-N2 and P3 ERP component have been regarded to reflect impulsivity, the interpretation of the changes in N2 and P3 ERP is inconclusive[18].
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