Abstract

We report the case of a patient with multiple sclerosis with congruent visual and auditory hallucinations of deceased familiar persons that lasted continuously for several days. Magnetic resonance imaging revealed an isolated, predominantly left-sided lesion in the periaqueductal segment of the mesencephalon. We propose that these hallucinations represent a bimodal variant of classic peduncular hallucinations, brought about by a deregulation of modulatory superior collicular activity and a release of cross-modal integrative functions of the superior temporal sulcus.

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