Abstract
Schwannomas are usually benign rare tumors that originating from Schwann cells of peripheral nerve sheaths. Presentation is generally varied and changed in a non-specific range from abdominal mass, flank pain to incidental findings. Herein we report 2 cases of retroperitoneal giant schwannomas with different clinical presentations, of whom one presented with vague abdominal pain, palpable abdominal mass for 4 years, swelling and bilateral hydronephrosis that caused by giant abdominal mass; the other one presented with right flank pain, rectal hemorrhage and lower extremities edema. Two patients were treated by complete surgical excision of masses. The histological and immunohistochemical diagnosis was reported as benign schwannoma. Both of patients are doing well and had no recurrence in 9 years and 28 months follow-up, respectively.
Highlights
Schwannomas are rare and usually benign tumors originating from Schwann cells of peripheral nerve sheaths.[1,2,3,4,5]
We report 2 cases of benign retroperitoneal giant schwannomas with different clinical presentations and their subsequent management, of whom one presented with vague abdominal pain, palpable abdominal mass for 4 years, swelling and bilateral hydronephrosis that caused by giant abdominal mass; one presented with right flank pain, rectal hemorrhage and lower extremities edema
A 46-year-old female patient presented with 2-year history of flank pain, one episode of rectal hemorrhage and increasingly edema at lower extremities
Summary
Schwannomas are usually benign rare tumors that originating from Schwann cells of peripheral nerve sheaths. Involvement of the urinary tract is rare, but involvement of the penis, testes, spermatic cord, and tunica vaginalis has been previously reported.[1,2,5] Most common presentation of the retroperitoneal schwannomas is vague abdominal or dull ache pain. The atypical presentations and giant retroperitoneal schwannomas are very rare.[2,4] we report 2 cases of benign retroperitoneal giant schwannomas with different clinical presentations and their subsequent management, of whom one presented with vague abdominal pain, palpable abdominal mass for 4 years, swelling and bilateral hydronephrosis that caused by giant abdominal mass; one presented with right flank pain, rectal hemorrhage and lower extremities edema.
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