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Abstract
Renal squamous cell cancer is one of the rare primary urothelial tumors with only a handful of cases reported in literature. Because of high grade, advanced and late presentation, they herald a grave prognosis. They are frequently associated with calculus disease, smoking, phenacetin consumption and foci of squamous metaplasia due to chronic irritation. Nephroureterectomy is the treatment of choice for such tumors. We hereby present a case of 59 year old female who presented with squamous cell cancer of renal pelvis. The case presented here is different from what has already been reported in literature, as the patient had no antecedent risk factors for renal squamous cell carcinoma. ------------------------------------------------- Cite this article as : Pahwa M, Pahwa AR, Girotra M, Chawla A. Atypical presentation of primary renal squamous cell cancer: a case report. Int J Cancer Ther Oncol 2014; 2 (1):02015. DOI: http://dx.doi.org/10.14319/ijcto.0201.5
Highlights
Renal squamous cell carcinoma (RSCC) is a rare cancer with a variable incidence of about 0.5–15% of all urothelial cancers.[1,2,3,4] The insidious onset of symptoms and lack of any pathognomonic sign leads to delay in diagnosis and treatment
Squamous cell carcinoma of the urinary tract is more frequently reported in urinary bladder and male urethra and rarely encountered in renal pelvis.[2,3,4,5]
The etiological factors which play in the genesis of this rare malignancy are strongly associated with phenacetin consumption, chronic renal calculi, pyelonephritis and squamous metaplasia
Summary
Renal squamous cell carcinoma (RSCC) is a rare cancer with a variable incidence of about 0.5–15% of all urothelial cancers.[1,2,3,4] The insidious onset of symptoms and lack of any pathognomonic sign leads to delay in diagnosis and treatment. We hereby present a case of renal squamous cancer with left nonfunctioning kidney in which there were no antecedent risk factors.
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