Atypical presentation of plasma cell leukaemia: A case report

Abstract

Introduction: Plasma cell leukaemia (PCL) is a rare blood disorder with an aggressive clinical course and dismal diagnosis. PCL is diagnosed based on the presence of an absolute plasma count of more than 2×109/L or 20% plasma cells in the peripheral blood. Initial presentation (primary PCL, pPCL) is 2–4% of myelomas. Secondary PCL is a leukaemic transformation occurring in approximately 1% of previously diagnosed plasma cell myeloma. The incidence of PCL is low, and this case presents a rare opportunity to describe the clinical and pathological characteristics of this disease.