Abstract

Background: Hypercalcemia is a common cl inical problem wi th an estimated pr evalence of 0.1% to 0.01% amonghospi tal ized patients and this can be ten times more in elder ly. T he a da ge, “s to nes , g r oans , b on es , an d ps y c hi a tri cov e rto nes ” i s o fte n us e d t o de s c ri b e t he s ym pto ms of hy p er p ar athy r oi di sm . Ho wev e r, 80% of el de rl y wi t h pri ma ryhyperparathyroidism present wi th asymptomatic or atypical hypercalcemia. We are classical ly taught that two mostcommon causes of hypercalcemia are mal ignancy and primary hyperparathyroidism (PHPT). Many case repor ts arepubl ished discussing the atypical presentation of hypercalcemia in elderly, meanwhi le, the review articlediscussing hypercalcemia in elderly is since 1988 (1) which also is the gold standard upon which, symptoms ofhypercalcemia in elderly are counted on and we can see that many cases are presented in a di fferent way now.This mini review includes case repor ts of atypical presentation of hypercalcemia in elderly aiming to establ ish anew sight about presentation in this age group.

Highlights

  • Hypercalcemia is a common clinical problem with an estimated pr evalence of 0.1% to 0.01% among hospitalized patients and this can be ten times more in elderly

  • The parathyroid scan showed hyperactive left upper parathyroid area. They stated “Despite the rarity of coexistence of primary hyperparathyroidism and multiple myeloma, bone marrow biopsy was obtained from our patient due to high suspicious features, i.e. weight loss, anemia, and thrombocytopenia even after confirming primary hyperparathyroidism

  • Hypernatremia was slowly corrected with hypotonic fluids, with improvement in his mental status over the 2 days. This was the first report of hypercalcemia associated with the use of a SLGT2 inhibitor

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Summary

Background

Hypercalcemia is a common clinical problem with an estimated pr evalence of 0.1% to 0.01% among hospitalized patients and this can be ten times more in elderly. Hypercalcemia is not a dihydroxyvitamin D level was elevated 131 pg/mL; common finding in patients with prostate cancer, but The parathyroid scan showed hyperactive left upper parathyroid area They stated “Despite the rarity of coexistence of primary hyperparathyroidism and multiple myeloma, bone marrow biopsy was obtained from our patient due to high suspicious features, i.e. weight loss, anemia, and thrombocytopenia even after confirming primary hyperparathyroidism. It revealed hypercellular marrow with decreased trilineage hematopoiesis and extensive involvement by plasma cells. The bone survey didn’t show evidence of focal lytic lesions

Atypical presentation of hypercalcemia underlying medications
Atypical presentation of hypercalcemia underlying infections
Atypical presentation of hypercalcemia underlying other causes
Findings
Conclusion
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