Abstract
We report a rare case of a 23-year-old male who presented with a four-week history of unilateral recurrent epistaxis and nasal obstruction. This was subsequently diagnosed as high-grade chondroblastic osteosarcoma of the maxillary antrum. Neo-adjuvant chemotherapy was commenced following a multidisciplinary team discussion. The disease progressed through first-line treatment. A radical surgical resection was not possible, and a palliative debulking procedure was performed. The literature comprehensively points towards an early surgical resection with suitable margins at the earliest possible stage. This case highlights that osteosarcoma of the maxilla can be challenging to diagnose and manage. Thus, a high index of suspicion and an early referral to a head and neck specialist is imperative to improve the long-term prognosis in such patients.
Highlights
A sarcoma is a malignant mesenchymal tumour associated with varied clinical presentations and pathological classifications
OS of the long bones age of onset tends to be a bimodal distribution from adolescence and the fifth decade, the most common cause of mortality is distant metastasis, painful swelling as well as the rarity of neuroparaesthesia amongst other factors [5,6]
We report the case of a 23-year-old male with a four-week history of recurrent epistaxis and unilateral nasal obstruction
Summary
A sarcoma is a malignant mesenchymal tumour associated with varied clinical presentations and pathological classifications. We report the case of a 23-year-old male with a four-week history of recurrent epistaxis and unilateral nasal obstruction. This was subsequently diagnosed as high-grade chondroblastic OS of the maxillary antrum. The episodes episodes of of epistaxis epistaxis were were usually usually mild mild and and self-limiting self-limiting after after aaperiod periodof oflocalised localisedpressure He described described increasing increasingpain painand andfullness fullnessover overhis hischeek cheekand andnasal nasal cavity. Scan of the Magnetic resonance angiogram (MRI) and computed tomographic (CT) scan of the nasal nasal sinuses sinuses showed a calcified osteoid sinonasal mass obstructing the right posterior nasal cavity. The head and neck cancer multidisciplinary team (MDT) meeting decided that an urgent nasal This revealed a possible diagnosis of grade III chondrosarcoma based polypectomy was warranted.
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