Abstract

Pancreatic cystic lesion (PCL) is a relatively low incidence of pancreatic disease. No clinical symptoms of PCL prevalence rate is 2.4% ~ 13.5% and has a tendency to increase with the increase of age. With the development of modern imaging technology and the improvement of people health consciousness, there has been a dramatic increase in the prevalence of PCL. PCLs involving a wide range of pathology can range from obviously benign to borderline malignant potential lesions to overt malignancy. Pancreatic cystadenocarcinoma belongs to one of the malignant tumor of PCLs, may be malignant from pancreatic cystadenoma, and it is clinically rare, accounting for only 1% of the malignant tumors of the pancreas. Preoperative diagnosis is difficult of the disease, it mostly need to postoperative pathological diagnosis. The main symptoms of pancreatic cystadenocarcinoma are dull pain or low back pain in the upper and middle abdomen, and mass in the upper abdomen. Abdominal pain is not intense, some patients only for the feeling of fullness discomfort. Other symptoms may include loss of appetite, nausea, indigestion, weight loss, jaundice, and in a few patients, gastrointestinal bleeding. In this paper, we report a rare case of pancreatic cystadenocarcinoma with a huge cystic lesion that grows rapidly in a short period of time in pregnant women, which preoperative diagnosis is considered pancreatic cystadenoma in the preoperative. Complete resection was performed and histological examination confirmed the diagnosis of pancreatic cystadenocarcinoma.

Highlights

  • Pancreatic cystic lesion (PCL) is a relatively uncommon condition

  • Pancreatic cystadenoma and Pancreatic cystadenocarcinoma are originated in the duct system and belong to the proliferative cyst

  • Combined with clinical differential diagnosis, pancreatic cystic tumor has been divided into two categories: one is serous cystic neoplasm (SCN), which is divided into serous cystadenoma and serous cystadenocarcinoma, and the other is mucinous cystic neoplasm (MCN), which is more rare than SCN, which is divided into mucinous cystadenoma and mucinous cystadenocarcinoma of the pancreas

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Summary

Introduction

Pancreatic cystic lesion (PCL) is a relatively uncommon condition. It is a neoplastic or nonneoplastic (single or multiple tumour-like) cystic lesion formed by pancreatic epithelial and/or stromal tissue, mainly including pancreatic cystic neoplasm (PCN) and pancreatic pseudocyst (PP). According to the 2010 WHO classification criteria, PCN mainly includes serous cystic neoplasm (SCN), mucinous cystic neoplasm (MCN), intraductal papillary mucinous neoplasm (IPMN) and solid pseudopapillaryneoplasm (SPN), etc. [1, 2] Due to the differences in clinical characteristics, imaging manifestations and pathological features of PCLs, it is still a big problem and challenge to improve the accuracy of preoperative diagnosis. Due to the different types of lesions between the potential risk of malignant transformation, there are huge differences in the corresponding treatment, follow-up strategy and clinical prognosis

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