Abstract
TO THE EDITOR: Hemolytic uremic syndrome (HUS) is characterized by a triad of non-immune hemolytic micro-angiopathic anemia, thrombocytopenia, and acute renal failure [1]. The majority of cases are typical HUS, caused by an enteric infection of Shiga toxin-producing Escherichia coli. Rarely, however, HUS is caused by dysregulation of the alternative pathway of the complement system and is known as atypical HUS (aHUS). One rare subtype is caused by anti-complement factor H (CFH) antibodies. Such patients are commonly treated by nephrologists; however, they will usually present to a hematologist for variable cytopenias. We report here one such patient who presented to us primarily for cytopenias.
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