Abstract
Background: It has been suggested that adolescents with conduct disorder (CD) may have a deficit in the affective and cognitive domains empathy, but studies exploring networks within the key brain regions of affective and cognitive empathy in adolescents with CD are lacking.Methods: Functional connectivity (FC) analyses among key brain regions of the affective and cognitive empathy with resting-state functional magnetic resonance imaging (fMRI) were conducted in 30 adolescent boys with CD and 33 demographically matched healthy controls (HCs).Results: Atypical FC within the key brain regions of affective empathy was not observed in CD adolescents. However, we found that CD adolescents showed decreased frontotemporal connectivity within the key brain regions of cognitive empathy in relation to HCs, that is, the FCs between right temporoparietal junction and ventromedial prefrontal cortex as well as dorsomedial prefrontal cortex.Conclusion: These findings may provide insight into neural mechanism underlying a cognitive empathy deficiency of CD adolescents from the perspective of FC.
Highlights
Conduct disorder (CD) is defined as a repetitive and persistent pattern of antisocial behavior in which the basic rights of others or social norms are violated (APA, 2013)
The group comparison results of analyses of covariance in functional connectivity (FC) involving the cognitive empathy network are reported in Table 2 and Figure 1C
In terms of the FC analyses, we found that CD adolescents exhibited decreased frontotemporal connectivity within the key brain regions of cognitive empathy, the vmPFC-rTPJ and dmPFC-rTPJ FCs
Summary
Conduct disorder (CD) is defined as a repetitive and persistent pattern of antisocial behavior in which the basic rights of others or social norms are violated (APA, 2013). The capacity to experience affective reactions to the observed experiences of others or share a “fellow feeling” has Atypical Cognitive Empathy in CD been described as affective empathy. The capacity to engage in the cognitive process of adopting another’s psychological point of view has been described as cognitive empathy, and its underlying processes include perspective taking and a more rational understanding of the emotions of others (Shamay-Tsoory, 2011). It has been suggested that adolescents with conduct disorder (CD) may have a deficit in the affective and cognitive domains empathy, but studies exploring networks within the key brain regions of affective and cognitive empathy in adolescents with CD are lacking
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
