Abstract
Choroid plexus tumors (CPTs) account for 2-4% of all brain neoplasms in the pediatric age group, and 14% of brain tumors occurring in the 1st year of life. On the basis of their histological features, as per 2016 WHO classification of tumors of the central nervous system, these tumors are classified as choroid plexus papilloma (CPP; WHO Grade I), atypical CPP (ACPP; WHO Grade II), and choroid plexus carcinoma (CPC; WHO Grade III). Atypical CPP was first recognized as a distinct entity in the 2007 WHO classification of tumors of the central nervous system. They were characterized by increased mitotic activity and a higher probability of recurrence as compared with CPP. The prognostic features of and clinical outcome rates for ACPP are between those displayed by CPP and CPC. Choroid plexus tumors can metastasize as solid nodules or as sub-arachnoid seeding, especially to the spine cord in patients with posterior fossa tumors. Metastases from CPP are rare and few cases have been reported. Whereas ACPP and CPC metastasize with greater frequency. We herewith report one child with ACPP managed by surgical excision and is currently under follow up with oncology.
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