Abstract
Atypical Chikungunya Virus Infections in Immunocompromised Patients
Highlights
Patient A, a 66-year-old Singaporean-Chinese man, had a history of chronic renal disease secondary to obstructive uropathy
An outbreak of Chikungunya virus (CHIKV) infection was reported at his workplace
Initial blood and urine cultures and serologic results were negative for dengue virus, but serum reverse transcription–PCR (RT-PCR) and indirect immunofluorescent assay for immunoglobulin G (IgG) (Euroimmun Medizinische Labordiagnostika, Lubeck, Germany) and IgM (CTK Biotech, Inc, San Diego, CA, USA) were positive for CHIKV [3,4]
Summary
Patient A, a 66-year-old Singaporean-Chinese man, had a history of chronic renal disease secondary to obstructive uropathy. An outbreak of CHIKV infection was reported at his workplace. He was admitted to National University Hospital, Singapore, in July 2008 with abdominal pain, vomiting, and fever of 1 day. His creatinine level was elevated at 921 μmol/L on admission.
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