Attractivity of male and female rats which are hormonally manipulated during early development and in adulthood

Abstract

Attractivity is one aspect of female sexuality relevant for the understanding of male-female sexual interactions. In a previous study, it was shown that intact males were equally attracted to early androgenized, gonadally intact females as to normally developed, estrous females. The present study was designed to investigate in what way hormones given in adulthood might influence attractivity of early androgenized females in adulthood. Specifically, we compared the attractivity of neonatally androgenized females (NeoTP) to the attractivity of normally developed females (NeoOIL), neonatally castrated males (NeoCASTR), and neonatally sham-castrated males (NeoSHAM) when different groups received either OIL, estradiol benzoate (EB) or testosterone propionate (TP) in adulthood. The male's preference to stay in the vicinity of one incentive in favor of the other was taken as an index of attractivity. The results show that, under the present hormonal conditions, NeoTP-females are generally less attractive than NeoOIL-females, more attractive than NeoSHAM-males, and equally attractive as NeoCASTR-males. TP-treated androgenized females were found to be equally attractive as TP-treated NeoSHAM-males. It is concluded that, relative to normally developed females, androgenized females become less attractive when the endogenous secretion of sex steriods is artifically controlled by gonadectomy and/or by administration of fixed amounts of sex steriods.