Abstract

ObjectivesWe examined 1) changes in smoking and vaping behavior and associated cotinine levels and health status among regular smokers who were first-time e-cigarette purchasers and 2) attitudes, intentions, and restrictions regarding e-cigarettes.MethodsWe conducted a pilot longitudinal study with assessments of the aforementioned factors and salivary cotinine at weeks 0, 4, and 8. Eligibility criteria included being ≥18 years old, smoking ≥25 of the last 30 days, smoking ≥5 cigarettes per day (cpd), smoking regularly ≥1 year, and not having started using e-cigarettes. Of 72 individuals screened, 40 consented, 36 completed the baseline survey, and 83.3% and 72.2% were retained at weeks 4 and 8, respectively.ResultsParticipants reduced cigarette consumption from baseline to week 4 and 8 (p’s < 0.001); 23.1% reported no cigarette use in the past month at week 8. There was no significant decrease in cotinine from baseline to week 4 or 8 (p’s = ns). At week 8, the majority reported improved health (65.4%), reduced smoker’s cough (57.7%), and improved sense of smell (53.8%) and taste (50.0%). The majority believed that e-cigarettes versus regular cigarettes have fewer health risks (97.2%) and that e-cigarettes have been shown to help smokers quit (80.6%) and reduce cigarette consumption (97.2%). In addition, the majority intended to use e-cigarettes as a complete replacement for regular cigarettes (69.4%) and reported no restriction on e-cigarette use in the home (63.9%) or car (80.6%).ConclusionsFuture research is needed to document the long-term impact on smoking behavior and health among cigarette smokers who initiate use of e-cigarettes.

Highlights

  • Electronic cigarettes are battery-powered devices that contain liquid that is vaporized with inhalation of the e-cigarette without any combustion or smoke and consist of a combination of propylene glycol, vegetable glycerine, various levels of nicotine, and flavor concentrates [1]

  • The emergence of e-cigarettes in the US may enable smoking cessation for some cigarette smokers because it addresses the biochemical and behavioral aspects of smoking addiction [3], the latter of which is largely unaddressed with traditional nicotine replacement therapies (NRT)

  • There is research needed in order to establish the effect of e-cigarettes on the smoking behavior of cigarette smokers in order to inform the regulation of e-cigarettes and their marketing

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Summary

Introduction

Electronic cigarettes (or e-cigarettes) are battery-powered devices that contain liquid that is vaporized with inhalation of the e-cigarette without any combustion or smoke and consist of a combination of propylene glycol, vegetable glycerine, various levels of nicotine, and flavor concentrates [1]. One study followed 40 current regular smokers (i.e., smoking 15 cigarettes per day [cpd]) experimenting with e-cigarettes for 24 weeks (27 retained at follow-up) [6] They reported a six-month point prevalence smoking cessation rate of 22.5%, with an additional 32.5% of smokers reducing their cigarette consumption by at least 50% [6]. In dual users who were still smoking at follow-up, cigarette consumption decreased by on average 5.3 cpd after one month, but remained unchanged between baseline and one-year follow-up. Each of these longitudinal studies of e-cigarette users demonstrated high rates of attrition

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