Abstract

BackgroundThere is increasing evidence that attitudes and beliefs are important in predicting adherence in depressive and bipolar disorders. However, such attitudes and beliefs on mood stabilizers have not been analysed by socio-demographic and clinical variables.MethodsThe Mood Stabilizer Compliance Questionnaire (MSQC) was mailed to a large population of patients with depressive or bipolar disorder representative of patients treated at their first contacts to hospital settings in Denmark.ResultsOf the 1005 recipients, 49.9 % responded to the letter and among these 256 indicated that they previously had been or currently were in treatment with a mood stabilizer. A large proportion of the patients (40 to 80 %) had non-correct views on the effect of mood stabilizers. Older patients consistently had a more negative view on the doctor-patient relationship, more non-correct views on the effect of mood stabilizers and a more negative view on mood stabilizers. There was no difference in the attitudes and beliefs according to the type of disorder (depressive or bipolar), the number of psychiatric hospitalisations or according to the type of the current doctor (general practitioner, private psychiatrist, community psychiatry doctor, hospital doctor, other doctor).ConclusionThere is a need of improving knowledge and attitudes toward diagnosis and treatment especially among elder patients as this may add to improve the prognosis of depressive and bipolar disorders.

Highlights

  • Medication non-adherence for depressive and bipolar disorders range from 10 to 60 %

  • Beliefs and expectations has in several studies been found to be associated with non-adherence to lithium [1,5,6] and a recent study concluded that attitudes and behaviours are better predictors of nonadherence to mood stabilizers than side effects of medication [7]

  • We have developed a questionnaire analogue to the ADQC to measure attitudes and beliefs concerning depressive and/or manic episodes and treatment with mood stabilizers, the Mood Stabilizer Compliance Questionnaire (MSCQ)

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Summary

Introduction

Medication non-adherence for depressive and bipolar disorders range from 10 to 60 % (median 40 %). It has recently been concluded in a review [1] that it seems as attitudes and beliefs are at least as important as sideeffects in predicting adherence in depressive and bipolar disorders [2,3,4]. We have developed a questionnaire analogue to the ADQC to measure attitudes and beliefs concerning depressive and/or manic episodes and treatment with mood stabilizers, the Mood Stabilizer Compliance Questionnaire (MSCQ). There is increasing evidence that attitudes and beliefs are important in predicting adherence in depressive and bipolar disorders Such attitudes and beliefs on mood stabilizers have not been analysed by socio-demographic and clinical variables

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