Attenuation during paradoxical sleep of signals from tooth pulp to thalamus

Abstract

Quantitative evaluation of the response of thalamic neurons to tooth pulp stimulation was made in chronically prepared cats. The latency, duration and intensity of the responses were measured from the post-stimulus time histograms to estimate, from various aspects, the alteration in the responsiveness during different phases of sleep and wakefulness. During slow wave sleep, tooth pulp-evoked impulses tended to be transmitted to the thalamus in a similar or slightly higher intensity compared to wakefulness. In contrast, during paradoxical sleep the signals were often attenuated in many aspects. The results seem to be in favor of the idea that the impairment of signal to noise ratio in a variety of neuronal networks is one of the characteristics of paradoxical sleep.