Abstract
This work proposes an attenuation correction method for x-ray fluorescence computed tomography (XFCT). The phantom is irradiated by a polychromatic cone-beam source produced by a conventional x-ray tube. X-ray fluorescence (XRF) photons are stimulated by the incident beam and are then collected by a photon counting detector placed on one side of the beamline. A flat-panel detector is placed along the beamline for detection of attenuation information. For quantitative reconstruction of XFCT images, the attenuation of incident photons as well as XRF photons in the phantom are estimated utilizing the transmission CT images. Simulation results show that the attenuation correction method proposed in this work significantly improves the accuracy of image reconstruction for XFCT, which enables quantitative identification of fluorescence materials in the objects.
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