Attention problems in relation to gestational age at birth and smallness for gestational age

Abstract

BackgroundWhile it is well established that very preterm birth (gestational age at birth <32weeks) is related to increased attention problems, there is still considerable uncertainty of the effects of moderate or late preterm birth or smallness for gestational age (SGA) on attention regulation. AimsTo investigate the impact of gestational age at birth and SGA, birth on child attention problems. Study designProspective longitudinal cohort study. SubjectsA total of 1435 children sampled from the Bavarian Longitudinal Study (BLS). Outcome measuresMain outcome variables were parent-reported attention problems and examiner-reported attention skills at 6 and 8years. Predictors were linked to attention outcomes using hierarchical regression analyses. ResultsGestational age at birth ranged from 25weeks to 41weeks. We found a quadratic effect of gestational age on attention problems (β6years=0.161, 95% CI=0.085; 0.236; β8years=0.211, 95% CI=0.135; 0.287), and attention skills at 6 and 8years (β6years=−0.178, 95% CI=−0.252; −0.104; β8years=−0.169, 95% CI=−0.243; −0.094). Elective caesarean birth did not predict child attention. In adjusted models, SGA was an additional risk factor for attention problems (β=0.080, 95% CI=0.026; 0.134), and attention skills (β=−0.091, 95% CI=−0.143; −0.039) at 6years but not at 8years after adjusting for child sex and family SES. ConclusionAdverse effects on attention are disproportionately higher at early gestations. In contrast, the impact of SGA status was found to be similar at all gestational ages but disappeared by 8years.